MICROEMULGEL: A NOVEL APPROACH FOR TOPICAL DRUG DELIVERY

Microemulgel: a novel approach for topical drug delivery

Topical drug delivery is mostly preferred for dermatological action.Topical dosage form such as cream, ointments, gels etc.has certain drawbacks like stability problems, stickiness, poor absorption as well as permeability.It has limitations in terms of drug solubility, residence here time, lipophilicity and permeability.To overcome this, a novel ap

read more

Myocardial Impact of NHE1 Regulation by Sildenafil

The cardiac Na+/H+ exchanger (NHE1) is a membrane glycoprotein fundamental for proper cell functioning due its multiple airpods in jacksonville housekeeping tasks, including regulation of intracellular pH, Na+ concentration, and cell volume.In the heart, hyperactivation of NHE1 has been linked to the development of different pathologies.Several stu

read more

A Robust Possibilistic Programming Approach for a Road-Rail Intermodal Routing Problem with Multiple Time Windows and Truck Operations Optimization under Carbon Cap-and-Trade Policy and Uncertainty

This study investigates a road-rail intermodal routing problem in a hub-and-spoke network.Carbon cap-and-trade policy is accommodated with redken shades eq 07m driftwood the routing to reduce carbon dioxide emissions.Multiple time windows are employed to enhance customer flexibility and achieve on-time pickup and delivery services.Road service flex

read more

Perioperative cancer cell dissemination detected with a real-time RT-PCR assay for EpCAM is not associated with worse prognosis in pancreatic ductal adenocarcinoma

Abstract Background Epithelial cell adhesion molecule (EpCAM) has been used as surrogate marker for the quantification of circulating tumour cells (CTC).Our aim was to prospectively study the value of a real-time RT-PCR assay for EpCAM detection in the peripheral blood and peritoneal cavity of patients undergoing pancreatectomy for pancreatic ducta

read more